Deepthi Sati was born in Chennai while brought up in Mumbai. Her father Bivyesh Sati hails from Nainital while mother Madhuri is a native of Pachalam. She did her schooling and college education at Mumbai.
She won the Miss Kerala title for the year 2012 and was among among the finalists of Femina Miss India 2014. Deepti Sati is made her movie debut as the lead heroine in the title role of Malayalam movie Nee-Na.